PUBLICATIONS

  1. Prickaerts, J, Kerckhoffs, J, Possemis, N, van Overveld, W, Verbeek, F, Grooters, T, Sambeth, A, Blokland, A. 2024. Roflumilast and cognition enhancement: A translational perspective. Biomed Pharmacother 181:117707. PMID:39591666
  2. Ashton, SM, Sambeth, A, Quaedflieg, CWEM. 2023. A mindful approach to controlling intrusive thoughts. Sci Rep 13:10966. PMID:37414828
  3. Handels, R, Grimm, S, Blokland, A, Possemis, N, Ramakers, I, Sambeth, A, Verhey, F, Vos, S, Joore, M, Prickaerts, J, Jönsson, L. 2023. The value of maintaining cognition in patients with mild cognitive impairment: The innovation headroom and potential cost-effectiveness of roflumilast. Alzheimers Dement 19:3458-3471. PMID:36808801
  4. Toth, M, Sambeth, A, Blokland, A. 2022. Age Effects on Old/New Recognition Memory Involving Abstract Figures and Non-words. Front Aging Neurosci 14:915055. PMID:35795236
  5. Toth, M, Sambeth, A, Blokland, A. 2022. The antimuscarinic agent biperiden selectively impairs recognition of abstract figures without affecting the processing of non-words. Hum Psychopharmacol 37:e2819. PMID:34533841
  6. Toth, M, Sambeth, A, Blokland, A. 2021. EEG Correlates of Old/New Discrimination Performance Involving Abstract Figures and Non-Words. Brain Sci 11:. PMID:34071488
  7. Bilderbeck, AC, Raslescu, A, Hernaus, D, Hayen, A, Umbricht, D, Pemberton, D, Tiller, J, Søgaard, B, Sambeth, A, van Amelsvoort, T, Reif, A, Papazisis, G, Pérez, V, Elices, M, Maurice, D, Bertaina-Anglade, V, Dawson, GR, Pollentier, S. 2020. Optimizing Behavioral Paradigms to Facilitate Development of New Treatments for Anhedonia and Reward Processing Deficits in Schizophrenia and Major Depressive Disorder: Study Protocol. Front Psychiatry 11:536112. PMID:33250788
  8. Borghans, L, Sambeth, A, Blokland, A. 2020. Biperiden Selectively Impairs Verbal Episodic Memory in a Dose- and Time-Dependent Manner in Healthy Subjects. J Clin Psychopharmacol 40:30-37. PMID:31834098
  9. Blokland, A, Van Duinen, MA, Sambeth, A, Heckman, PRA, Tsai, M, Lahu, G, Uz, T, Prickaerts, J. 2019. Acute treatment with the PDE4 inhibitor roflumilast improves verbal word memory in healthy old individuals: a double-blind placebo-controlled study. Neurobiol Aging 77:37-43. PMID:30776650
  10. Heckman, P, Blokland, A, Sambeth, A. 2019. No interaction between rivastigmine and citalopram on memory and novelty processing in healthy human volunteers. J Psychopharmacol 33:210-218. PMID:30226087
  11. Borghans, LGJM, Sambeth, A, Prickaerts, J, Ramaekers, JG, Blokland, A. 2018. The effects of the soluble guanylate cyclase stimulator riociguat on memory performance in healthy volunteers with a biperiden-induced memory impairment. Psychopharmacology (Berl) 235:2407-2416. PMID:29882087
  12. Van Duinen, MA, Sambeth, A, Heckman, PRA, Smit, S, Tsai, M, Lahu, G, Uz, T, Blokland, A, Prickaerts, J. 2018. Acute administration of roflumilast enhances immediate recall of verbal word memory in healthy young adults. Neuropharmacology 131:31-38. PMID:29241652
  13. Heckman, PRA, Van Duinen, MA, Blokland, A, Uz, T, Prickaerts, J, Sambeth, A. 2018. Acute administration of roflumilast enhances sensory gating in healthy young humans in a randomized trial. Psychopharmacology (Berl) 235:301-308. PMID:29098341
  14. Caldenhove, S, Borghans, LGJM, Blokland, A, Sambeth, A. 2017. Role of acetylcholine and serotonin in novelty processing using an oddball paradigm. Behav Brain Res 331:199-204. PMID:28511977
  15. Borghans, LG, Blokland, A, Sambeth, A. 2017. Effects of biperiden and acute tryptophan depletion and their combination on verbal word memory and EEG. Psychopharmacology (Berl) 234:1135-1143. PMID:28210777
  16. Blokland, A, Sambeth, A, Prickaerts, J, Riedel, WJ. 2016. Why an M1 Antagonist Could Be a More Selective Model for Memory Impairment than Scopolamine. Front Neurol 7:167. PMID:27746762
  17. Kuypers, KP, Theunissen, EL, van Wel, JH, de Sousa Fernandes Perna, EB, Linssen, A, Sambeth, A, Schultz, BG, Ramaekers, JG. 2016. Verbal Memory Impairment in Polydrug Ecstasy Users: A Clinical Perspective. PLoS One 11:e0149438. PMID:26907605
  18. Vanmierlo, T, Creemers, P, Akkerman, S, van Duinen, M, Sambeth, A, De Vry, J, Uz, T, Blokland, A, Prickaerts, J. 2016. The PDE4 inhibitor roflumilast improves memory in rodents at non-emetic doses. Behav Brain Res 303:26-33. PMID:26794595
  19. Duinen, MV, Reneerkens, OA, Lambrecht, L, Sambeth, A, Rutten, BP, Os, JV, Blokland, A, Prickaerts, J. 2015. Treatment of Cognitive Impairment in Schizophrenia: Potential Value of Phosphodiesterase Inhibitors in Prefrontal Dysfunction. Curr Pharm Des 21:3813-28. PMID:26044976
  20. Blokland, A, Prickaerts, J, van Duinen, M, Sambeth, A. 2015. The use of EEG parameters as predictors of drug effects on cognition. Eur J Pharmacol 759:163-8. PMID:25823806
  21. Sambeth, A, Riedel, WJ, Klinkenberg, I, Kähkönen, S, Blokland, A. 2015. Biperiden selectively induces memory impairment in healthy volunteers: no interaction with citalopram. Psychopharmacology (Berl) 232:1887-97. PMID:25466702
  22. Theunissen, EL, Heckman, P, de Sousa Fernandes Perna, EB, Kuypers, KP, Sambeth, A, Blokland, A, Prickaerts, J, Toennes, SW, Ramaekers, JG. 2015. Rivastigmine but not vardenafil reverses cannabis-induced impairment of verbal memory in healthy humans. Psychopharmacology (Berl) 232:343-53. PMID:24998257
  23. Linssen, AM, Sambeth, A, Vuurman, EF, Riedel, WJ. 2014. Cognitive effects of methylphenidate in healthy volunteers: a review of single dose studies. Int J Neuropsychopharmacol 17:961-77. PMID:24423151
  24. Quaedflieg, CW, Münte, S, Kalso, E, Sambeth, A. 2014. Effects of remifentanil on processing of auditory stimuli: a combined MEG/EEG study. J Psychopharmacol 28:39-48. PMID:24257810
  25. Linssen, AM, Sambeth, A, Vuurman, EF, Riedel, WJ. 2014. Cognitive effects of methylphenidate and levodopa in healthy volunteers. Eur Neuropsychopharmacol 24:200-6. PMID:24119823
  26. Partanen, E, Kujala, T, Näätänen, R, Liitola, A, Sambeth, A, Huotilainen, M. 2013. Learning-induced neural plasticity of speech processing before birth. Proc Natl Acad Sci U S A 110:15145-50. PMID:23980148
  27. Münte, S, Quaedflieg, CW, Sambeth, A, Wang, M, Kalso, E. 2013. Effects of remifentanil on cognitive and psychomotor functioning and mood. Br J Anaesth 111:517-8. PMID:23946371
  28. Reneerkens, OA, Sambeth, A, Blokland, A, Prickaerts, J. 2013. PDE2 and PDE10, but not PDE5, inhibition affect basic auditory information processing in rats. Behav Brain Res 250:251-6. PMID:23688598
  29. Reneerkens, OA, Sambeth, A, Ramaekers, JG, Steinbusch, HW, Blokland, A, Prickaerts, J. 2013. The effects of the phosphodiesterase type 5 inhibitor vardenafil on cognitive performance in healthy adults: a behavioral-electroencephalography study. J Psychopharmacol 27:600-8. PMID:23427190
  30. Conen, S, Theunissen, EL, Vermeeren, A, Sambeth, A, Ramaekers, JG. 2013. Central nervous system-impairing effects of hydroxyzine as a function of histamine availability. J Clin Psychopharmacol 33:276-9. PMID:23422368
  31. Klinkenberg, I, Blokland, A, Riedel, WJ, Sambeth, A. 2013. Cholinergic modulation of auditory processing, sensory gating and novelty detection in human participants. Psychopharmacology (Berl) 225:903-21. PMID:23052568
  32. Linssen, AM, Sambeth, A, Riedel, WJ, Vuurman, EF. 2013. Higher, faster, stronger: the effect of dynamic stimuli on response preparation and CNV amplitude. Behav Brain Res 237:308-12. PMID:23041181
  33. Klinkenberg, I, Sambeth, A, Blokland, A. 2013. Cholinergic gating of hippocampal auditory evoked potentials in freely moving rats. Eur Neuropsychopharmacol 23:988-97. PMID:22974558
  34. Reneerkens, OA, Sambeth, A, Van Duinen, MA, Blokland, A, Steinbusch, HW, Prickaerts, J. 2013. The PDE5 inhibitor vardenafil does not affect auditory sensory gating in rats and humans. Psychopharmacology (Berl) 225:303-12. PMID:22855271
  35. Nevalainen, P, Pihko, E, Metsäranta, M, Sambeth, A, Wikström, H, Okada, Y, Autti, T, Lauronen, L. 2012. Evoked magnetic fields from primary and secondary somatosensory cortices: a reliable tool for assessment of cortical processing in the neonatal period. Clin Neurophysiol 123:2377-83. PMID:22749463
  36. Linssen, AM, Vuurman, EF, Sambeth, A, Riedel, WJ. 2012. Methylphenidate produces selective enhancement of declarative memory consolidation in healthy volunteers. Psychopharmacology (Berl) 221:611-9. PMID:22169884
  37. Klinkenberg, I, Blokland, A, Riedel, W, Sambeth, A. 2012. Human electrophysiological correlates of learned irrelevance: effects of the muscarinic M1 antagonist biperiden. Int J Neuropsychopharmacol 15:1375-85. PMID:22094124
  38. Theunissen, EL, Kauert, GF, Toennes, SW, Moeller, MR, Sambeth, A, Blanchard, MM, Ramaekers, JG. 2012. Neurophysiological functioning of occasional and heavy cannabis users during THC intoxication. Psychopharmacology (Berl) 220:341-50. PMID:21975580
  39. Linssen, AM, Vuurman, EF, Sambeth, A, Nave, S, Spooren, W, Vargas, G, Santarelli, L, Riedel, WJ. 2011. Contingent negative variation as a dopaminergic biomarker: evidence from dose-related effects of methylphenidate. Psychopharmacology (Berl) 218:533-42. PMID:21597989
  40. Simons, CJ, Sambeth, A, Krabbendam, L, Pfeifer, S, van Os, J, Riedel, WJ. 2011. Auditory P300 and N100 components as intermediate phenotypes for psychotic disorder: familial liability and reliability. Clin Neurophysiol 122:1984-90. PMID:21459037
  41. Klinkenberg, I, Sambeth, A, Blokland, A. 2011. Acetylcholine and attention. Behav Brain Res 221:430-42. PMID:21108972
  42. Evers, EA, Sambeth, A, Ramaekers, JG, Riedel, WJ, van der Veen, FM. 2010. The effects of acute tryptophan depletion on brain activation during cognition and emotional processing in healthy volunteers. Curr Pharm Des 16:1998-2011. PMID:20370668
  43. Linssen, AM, Riedel, WJ, Sambeth, A. 2011. Effects of tyrosine/phenylalanine depletion on electrophysiological correlates of memory in healthy volunteers. J Psychopharmacol 25:230-8. PMID:19939876
  44. Mendelsohn, D, Riedel, WJ, Sambeth, A. 2009. Effects of acute tryptophan depletion on memory, attention and executive functions: a systematic review. Neurosci Biobehav Rev 33:926-52. PMID:19428501
  45. van Ruitenbeek, P, Sambeth, A, Vermeeren, A, Young, SN, Riedel, WJ. 2009. Effects of L-histidine depletion and L-tyrosine/L-phenylalanine depletion on sensory and motor processes in healthy volunteers. Br J Pharmacol 157:92-103. PMID:19413574
  46. van Ruitenbeek, P, Vermeeren, A, Smulders, FT, Sambeth, A, Riedel, WJ. 2009. Histamine H1 receptor blockade predominantly impairs sensory processes in human sensorimotor performance. Br J Pharmacol 157:76-85. PMID:19220286
  47. Sambeth, A, Meeter, M, Blokland, A. 2009. Hippocampal theta frequency and novelty. Hippocampus 19:407-8; author reply 409-10. PMID:19212942
  48. Sambeth, A, Pakarinen, S, Ruohio, K, Fellman, V, van Zuijen, TL, Huotilainen, M. 2009. Change detection in newborns using a multiple deviant paradigm: a study using magnetoencephalography. Clin Neurophysiol 120:530-8. PMID:19211303
  49. Sambeth, A, Riedel, WJ, Tillie, DE, Blokland, A, Postma, A, Schmitt, JA. 2009. Memory impairments in humans after acute tryptophan depletion using a novel gelatin-based protein drink. J Psychopharmacol 23:56-64. PMID:18515454
  50. Nevalainen, P, Lauronen, L, Sambeth, A, Wikström, H, Okada, Y, Pihko, E. 2008. Somatosensory evoked magnetic fields from the primary and secondary somatosensory cortices in healthy newborns. Neuroimage 40:738-745. PMID:18234514
  51. Sambeth, A, Ruohio, K, Alku, P, Fellman, V, Huotilainen, M. 2008. Sleeping newborns extract prosody from continuous speech. Clin Neurophysiol 119:332-41. PMID:18069059
  52. Sambeth, A, Riedel, WJ, Smits, LT, Blokland, A. 2007. Cholinergic drugs affect novel object recognition in rats: relation with hippocampal EEG?. Eur J Pharmacol 572:151-9. PMID:17659275
  53. Sambeth, A, Blokland, A, Harmer, CJ, Kilkens, TO, Nathan, PJ, Porter, RJ, Schmitt, JA, Scholtissen, B, Sobczak, S, Young, AH, Riedel, WJ. 2007. Sex differences in the effect of acute tryptophan depletion on declarative episodic memory: a pooled analysis of nine studies. Neurosci Biobehav Rev 31:516-29. PMID:17229463
  54. Sambeth, A, Huotilainen, M, Kushnerenko, E, Fellman, V, Pihko, E. 2006. Newborns discriminate novel from harmonic sounds: a study using magnetoencephalography. Clin Neurophysiol 117:496-503. PMID:16426892
  55. Pihko, E, Sambeth, A, Leppänen, PH, Okada, Y, Lauronen, L. 2004. Auditory evoked magnetic fields to speech stimuli in newborns--effect of sleep stages. Neurol Clin Neurophysiol 2004:6. PMID:16012690
  56. Sambeth, A, Maes, JH, Quian Quiroga, R, Coenen, AM. 2004. Effects of stimulus repetitions on the event-related potential of humans and rats. Int J Psychophysiol 53:197-205. PMID:15246673
  57. Sambeth, A, Maes, JH, Brankack, J. 2004. With long intervals, inter-stimulus interval is the critical determinant of the human P300 amplitude. Neurosci Lett 359:143-6. PMID:15050684
  58. Sambeth, A, Maes, JH, Quian Quiroga, R, Van Rijn, CM, Coenen, AM. 2004. Enhanced re-habituation of the orienting response of the human event-related potential. Neurosci Lett 356:103-6. PMID:14746874
  59. Sambeth, A, Maes, JH, Van Luijtelaar, G, Molenkamp, IB, Jongsma, ML, Van Rijn, CM. 2003. Auditory event-related potentials in humans and rats: effects of task manipulation. Psychophysiology 40:60-8. PMID:12751804
  60. Jongsma, ML, van Rijn, CM, van Egmond, J, van Schaijk, WJ, Sambeth, A, Coenen, AM. 2000. The influence of diazepam on the electroencephalogram-evoked potential interrelation in rats. Neurosci Lett 293:83-6. PMID:11027839